Recalcitrant Pyoderma Gangrenosum and Subcorneal Pustular Dermatosis Successfully Treated With Adalimumab
نویسندگان
چکیده
منابع مشابه
Pustular penile pyoderma gangrenosum successfully treated with topical tacrolimus ointment.
© 2012 The Authors. doi: 10.2340/00015555-1167 Journal Compilation © 2012 Acta Dermato-Venereologica. ISSN 0001-5555 Penile pyoderma gangrenosum (PPG) is an uncommon, non-infectious and idiopathic skin disease. Therapeutic options include topical or systemic corticosteroids or other systemically administered immunomodulatory drugs (1). We described here an eruption of pustular PPG, which was tr...
متن کاملAdalimumab Therapy for Recalcitrant Pyoderma Gangrenosum
OBJECTIVE To describe a patient with treatment-refractory pyoderma gangrenosum and the outcome of a novel therapeutic approach. METHODS Case report and review of the literature. RESULTS A patient with inflammatory bowel disease developed severe pyoderma gangrenosum while receiving treatment with the chimeric anti-TNF-alpha antibody infliximab. Despite subsequent trials of numerous immunosup...
متن کاملSubcorneal pustular dermatosis.
Subcorneal dermatosis is a chronic relapsing pustular eruption which has been recognised for 20 years. The diagnosis can be made only by combining the clinical features of a recurrent eruption mainly on the trunk which spares the mucosae and has the histological appearance of a subcorneal bullae filled with polymorphonuclear leucocytes situated on the surface of normal epidermis. No immunofluor...
متن کاملSubcorneal pustular dermatosis in the pediatric age*
Subcorneal pustular dermatosis is a rare pustular eruption which occurs mainly in middle-aged women and rarely during childhood. We report a case of a 15-year-old female with a 4-year history of pustular lesions on the proximal region of the upper limbs with subsequent impairment of the trunk. Physical examination revealed small pustules distributed on the trunk and proximal region of the limbs...
متن کاملSubcorneal pustular dermatosis an immnohisto-pathological perspective.
UNLABELLED Subcorneal pustular dermatosis (SPD) represents a chronic, relapsing sterile pustular eruption, involving the trunk and flexoral proximal extremities. A 54-year-old female presented with recurrent, flaccid pustules measuring several millimeters in diameter, on normal and mildly erythematous skin of the groin and submammary areas. Biopsies for hematoxylin and eosin (H&E) examination, ...
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ژورنال
عنوان ژورنال: Actas Dermo-Sifiliográficas (English Edition)
سال: 2020
ISSN: 1578-2190
DOI: 10.1016/j.adengl.2020.10.018